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It is very important that ghrelin has to be acylated by ghrelin O-acyl-transferase (GOAT), which binds a fatty acid side chain (C8) to serine 3 of ghrelin, forming acyl ghrelin, the active form that acts on its receptor, a G-protein-coupled receptor (GHSR-1a)
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doi: 10.1038/ncomms2266 93 KasaiC.SugimotoK.MoritaniI.TanakaJ.OyaY.InoueH.et al
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