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As other covalent modulators, quinones can show opposing effects leading to cytoxicity or cytoprotection [26,27] depending on the dose, exposure time and intrinsic electrophilicity of the quinone, as shown in Figure 6
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Inhibition of Th1/Th17 responses via suppression of STAT1 and STAT3 activation contributes to the amelioration of murine experimental colitis by a natural flavonoid glucoside icariin
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