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In vitro and in vivo experiments demonstrated that these nanoparticles exhibited excellent targeting to M1 macrophages, significantly increasing drug retention in RA joints and further inhibiting inflammation, thereby demonstrating substantial therapeutic effects

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A 2023 meta-analysis found that NAC improved some metabolic markers in women with PCOS, including fasting glucose.21 More recent research has also explored NAC alongside ovulation-induction treatments, suggesting possible benefits for endocrine and reproductive outcomes.20 While the findings are encouraging, researchers are still working to determine which women are most likely to benefit and how NAC compares with established treatments such as metformin