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19,360 Although, the novel modulator therapy provided unprecedented clinical benefits for over 90% of patients with CF, ~10% of CF patients (including those with large CFTR deletions that include the promoter and intronic regions of the gene) are ineligible for CFTR modulator therapy

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ROS may be important mediators of cellular injury during COVID-19 sepsis (Silvagno et al., 2020), either following macromolecular damage or by hindering extracellular and intracellular regulatory processes