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The cytochrome P450 enzymes CYP2C19, CYP2B6, and CYP3A4 perform an initial desulfuration process to produce the appropriate oxon metabolite, which is then hydrolyzed via PON1 to produce DAP ( 5 Toxicokinetics of cocktail mixtures 5.1 Mechanism(s) of interaction of EDCs Humans are subjected to exposure to environmental chemicals that are present in infinite number of combinations
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